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Evaluation of the Effect of Melatonin and Sour Cherry Concentrate Combination on Preoperative Anxiety in Children

Evaluation of the Effect of Melatonin and Sour Cherry Concentrate Combination on Preoperative Anxiety in Children: A Randomized Clinical Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220429054694N3
Enrollment
156
Registered
2025-08-22
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative anxiety. Anxiety disorder due to known physiological condition

Interventions

Intervention 1: Control group: Patients who receive drinking water orally without any additives except for routine care. Intervention 2: Intervention group: Patients who receive a melatonin tablet (ma

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 16 Years

Inclusion criteria

Inclusion criteria: Children aged 3 to 16 years Indications for elective urogenital surgery According to the American Society of Anesthesiologists (ASA) criteria, be classified in class one or two

Exclusion criteria

Exclusion criteria: Patients with epilepsy and serious neurological disorders based on history Patients with type 1 diabetes based on history Patients taking warfarin or coagulation disorders based on history Patients with high blood pressure based on history

Design outcomes

Primary

MeasureTime frame
Comparison of preoperative anxiety and anxiety changes before induction of anesthesia in three groups. Timepoint: 2 hours before anesthesia induction and during anesthesia induction. Method of measurement: Examining the level of anxiety with the Modified Yale Preoperative Anxiety Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamane Sadat Asadi Kakhki

Mashhad University of Medical Sciences

smn.s.asadi@gmail.com+98 51 3892 9433

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026