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Double blinded clinical trial: The effect of irrigating the surgical site with triamcinolone during surgery in reducing pain and inflammation after upper blepharoplasty

Double blinded clinical trial: The effect of irrigating the surgical site with triamcinolone during surgery in reducing pain and inflammation after upper blepharoplasty

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220424054640N1
Enrollment
21
Registered
2022-05-04
Start date
2022-06-21
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cosmetic Surgery- blepharoplasty. Other plastic surgery for unacceptable cosmetic appearance

Interventions

Intervention group: One patient‘s eye (left or right): irrigating 1cc triamcinolone 40 mg/kg in wound at the end of upper blepharoplasty.

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: All subjects that candidate for bilateral upper blepharoplasty, after explanation of treatment and study steps and obtaining informed consent.

Exclusion criteria

Exclusion criteria: Language or communication problem Uncertainty about follow-up History of previous surgery or trauma Asymmetry in the appearance of the eyes and eyelids on both sides (left and right) Inflammatory eye disease (uveitis, ocular thyroid, orbital inflammation)

Design outcomes

Primary

MeasureTime frame
Decreasing ecchymosis: Use the SPREE questionnaire which is filled by the physician. ?. No ecchymosis 1. Ecchymosis up to 1/3 of the lower or upper eyelid 2. Ecchymosis up to 2/3 of the lower or upper eyelid 3.Ecchymosis of more than two-thirds of the upper or lower eyelid. Timepoint: 6 hours, 24 to 72 hours, 7 days and 30 days after surgery. Method of measurement: Surgeon Periorbital Rating of Edema and Ecchymosis for rating ecchymosis.;Decreasing inflammation: Use the SPREE questionnaire which is filled by the physician . 1. Inflammation without iris involvement of the eyelid 2. Slight coverage of the iris by the inflamed eyelid 3. Complete coverage of the iris by the inflamed eyelid 4. Complete eye closure due to eyelid inflammation. Timepoint: 6 hours, 24 to 72 hours, 7 days and 30 days after surgery. Method of measurement: Surgeon Periorbital Rating of Edema and Ecchymosis for rating inflammation.;Decreasing Pain: Patients are asked to rate their pain according to the VAS scale. VAS is a 10 cm line printed on a piece of paper with a marker at the end. on the one hand ; (0) means painless; and at the other hand (10) means Worst pain. Timepoint: 6 hours, 24 to 72 hours, 7 days and 30 days after surgery. Method of measurement: Visual Analogue Scale for rating pain.;Decreasing edema and ecchymosis :Patients are asked to rate their edema and ecchymosis according to the VAS scale. VAS is a 10 cm line printed on a piece of paper with a marker at the end. on the one hand ; (0) means lack of edema and ecchymosis; and at the other hand (10) means Worst edema and ecchymosis. Timepoint: 6 hours, 24 to 72 hours, 7 days and 30 days after surgery. Method of measurement: Visual Analogue Scale for rating edema and ecchymosis.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. nasser karimi

Iran University of Medical Sciences

drnasserkarimi@gmail.com+98 21 6655 8811

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026