The relationship between oropharyngeal administration of breast milk and early outcomes in premature infants with a birth weight of less than 1500 grams.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220424054629N1

Enrollment

Registered

2023-05-09

Start date

2023-06-22

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Necrotizing enterocolitis. Condition 2: oral colostrum. Condition 3: Neonatal sepsis. Condition 4: Retinopaty of prematurity. Condition 5: Intraventricular hemorrhage. Condition 6: Bronchopulmonary dysplasia. Condition 7: Neonatal death. Condition 8: ventilator associated pneumonia.

Interventions

Intervention 1: Intervention group: In this group, babies will receive 8 drops equivalent to 0.2 cc of warm milk expressed by their mother every 3 hours. This amount of milk will be dripped 4 drops on

Eligibility

Sex/Gender

All

Age

1 Days to No maximum

Inclusion criteria

Inclusion criteria: no sever congenital anomalies birth weight below 1500 gr capability of protocol administration in the first 96 hours

Exclusion criteria

Exclusion criteria: Congenital Anomalies Gastrointestinal problems that are for contraindication to nutrition, such as esophageal atresia Neonatal asphyxia Maternal HIV infection Maternal history of substance abuse Triple gestation or more

Design outcomes

Primary

Measure	Time frame
Neonatal death. Timepoint: During hospitalization. Method of measurement: Clinical documentation.;Neonatal Sepsis. Timepoint: During hospitalization. Method of measurement: Clinical and paraclinic documentation.;Retinopathy of prematurity. Timepoint: During hospitalization. Method of measurement: Physical examination.;Intraventricular hemorrhage. Timepoint: During hospitalization. Method of measurement: Brain sonography.;Ventilator associated pneumonia. Timepoint: During hospitalization. Method of measurement: Clinical and paraclinical documentaion.;Time to reach fullfeed. Timepoint: During hospitalization. Method of measurement: Clinical documentaion.;Necrotizing entrocolitis. Timepoint: During hospitalization. Method of measurement: Clinical documentaion.;Hospitalization duration. Timepoint: During hospitalization. Method of measurement: Clinical doccumenation.;Oral colostrom intake. Timepoint: During the first 96 hours of life. Method of measurement: Clinical documentation.;Bronchopulmonary dysplaisa. Timepoint: During hospitalization. Method of measurement: Clinical and paraclinic documentation.	—

Measure

Time frame

Neonatal death. Timepoint: During hospitalization. Method of measurement: Clinical documentation.;Neonatal Sepsis. Timepoint: During hospitalization. Method of measurement: Clinical and paraclinic documentation.;Retinopathy of prematurity. Timepoint: During hospitalization. Method of measurement: Physical examination.;Intraventricular hemorrhage. Timepoint: During hospitalization. Method of measurement: Brain sonography.;Ventilator associated pneumonia. Timepoint: During hospitalization. Method of measurement: Clinical and paraclinical documentaion.;Time to reach fullfeed. Timepoint: During hospitalization. Method of measurement: Clinical documentaion.;Necrotizing entrocolitis. Timepoint: During hospitalization. Method of measurement: Clinical documentaion.;Hospitalization duration. Timepoint: During hospitalization. Method of measurement: Clinical doccumenation.;Oral colostrom intake. Timepoint: During the first 96 hours of life. Method of measurement: Clinical documentation.;Bronchopulmonary dysplaisa. Timepoint: During hospitalization. Method of measurement: Clinical and paraclinic documentation.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSedigheh Tehranchi

Shahid Beheshti University of Medical Sciences

drsedighehtehranchi@gmail.com+98 21 25719

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026