Comparison of the effect of high-power and low-power laser and drug therapy in improving the symptoms, function and sonographic findings in patients with carpal tunnel syndrome

Evaluation of the comparative effect of high-power and low-power laser and drug therapy in improving the symptoms, function and sonographic findings in patients with mild to moderate carpal tunnel syndrome

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220423054620N1

Enrollment

Registered

2022-06-08

Start date

2022-06-22

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal tunnel syndrome. Carpal tunnel syndrome

Interventions

Intervention 1: Control group: In this group, patients have routinely prescribed wrist splints, in addition to vitamin B1 and gabapentin 100 mg for two weeks. Intervention 2: Intervention group 1: In

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with mild to moderate carpal tunnel syndrome Age category over 18 years No history of injection in the carpal tunnel in a recent month Consent to participate in the study

Exclusion criteria

Exclusion criteria: Having neuropathic diseases Having systemic diseases that affect treatment (such as hypothyroidism, diabetes, rheumatism) Having a history of carpal tunnel surgery Pregnancy

Design outcomes

Primary

Measure	Time frame
Symptoms. Timepoint: Before treatment, one month and three months after treatment. Method of measurement: Boston Questionnaire.;Functional status. Timepoint: Before treatment, one month and three months after treatment. Method of measurement: Boston Questionnaire.;Pain. Timepoint: Before treatment, one month and three months after treatment. Method of measurement: Visual Analog Scale (VAS).;Nerve Conduction Velocity (NCV) across wrist. Timepoint: Before treatment and three months after treatment. Method of measurement: Nerve and muscle strip.;Sensory nerve action potential (SNAP) across wrist. Timepoint: Before treatment and three months after treatment. Method of measurement: Nerve and muscle strip.;Compound Muscle Action Potential (CMAP) across wrist. Timepoint: Before treatment and three months after treatment. Method of measurement: Nerve and muscle strip.;Cross-sectional area (CSA) carpal tunnel. Timepoint: Before treatment and three months after treatment. Method of measurement: Sonography.	—

Measure

Time frame

Symptoms. Timepoint: Before treatment, one month and three months after treatment. Method of measurement: Boston Questionnaire.;Functional status. Timepoint: Before treatment, one month and three months after treatment. Method of measurement: Boston Questionnaire.;Pain. Timepoint: Before treatment, one month and three months after treatment. Method of measurement: Visual Analog Scale (VAS).;Nerve Conduction Velocity (NCV) across wrist. Timepoint: Before treatment and three months after treatment. Method of measurement: Nerve and muscle strip.;Sensory nerve action potential (SNAP) across wrist. Timepoint: Before treatment and three months after treatment. Method of measurement: Nerve and muscle strip.;Compound Muscle Action Potential (CMAP) across wrist. Timepoint: Before treatment and three months after treatment. Method of measurement: Nerve and muscle strip.;Cross-sectional area (CSA) carpal tunnel. Timepoint: Before treatment and three months after treatment. Method of measurement: Sonography.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRaziye Maghroori

Esfahan University of Medical Sciences

maghroori@mui.ac.ir+98 31 3233 0091

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026