Comparison effect of Naproxen and Meloxicam after fully occluded mandibular third molar surgery

A comparative study of the effect of Meloxicam 7.5 mg and Naproxen 250 mg in reducing complications after fully occluded mandibular third molar surgery;a split-mouth study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220418054585N1

Enrollment

Registered

2022-07-17

Start date

2022-05-20

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extraction of fully occluded mandibular third molar surgery.

Interventions

Intervention group: After the third molar tooth surgery in one side of the mandible, meloxicam 7.5 mg will be prescribed, and after the impacted tooth surgery on the other side of the mandible, naprox

Eligibility

Sex/Gender

All

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Patients are in the age range of 20 to 35 years Have no history of any systemic disease It also has good oral hygiene Have the consent to enter the study.

Exclusion criteria

Exclusion criteria: Patients who are pregnant, Has a history of drug addiction and analgesics Have used painkillers 24 hours before the operation The root of the impacted tooth is in contact with the mandibular nerve

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 12 and 24 hours after surgery,. Method of measurement: The Visual Analogue Scale is used to assess pain before surgery, 12 and 24 hours after. This scale includes derivation from zero to 10. Zero means no pain and 10 means too much pain, forcing the person to rest at home. The patient will be informed about the pain scale before surgery and will be asked by phone 12 and 24 hours after surgery.;Swelling. Timepoint: 2 and 7 days after surgery. Method of measurement: . To evaluate swelling before surgery, 2 and 7 days later, Gabka and Matsura methods are used. will be. In this method, the distance between the outer corner of the eye and the mandibular angle, between the tragus and the outer corner of the mouth, and between the tragus and the soft tissue of the pogunion is measured in millimeters. Then the average of these three numbers is calculated and inflation is obtained.;Trismus. Timepoint: 2 and 7 days after surgery. Method of measurement: A ruler will be used to check for trismus before surgery, 2 and 7 days after. The distances between the upper and lower centers before and after the operation are measured using a ruler.	—

Measure

Time frame

Pain. Timepoint: 12 and 24 hours after surgery,. Method of measurement: The Visual Analogue Scale is used to assess pain before surgery, 12 and 24 hours after. This scale includes derivation from zero to 10. Zero means no pain and 10 means too much pain, forcing the person to rest at home. The patient will be informed about the pain scale before surgery and will be asked by phone 12 and 24 hours after surgery.;Swelling. Timepoint: 2 and 7 days after surgery. Method of measurement: . To evaluate swelling before surgery, 2 and 7 days later, Gabka and Matsura methods are used. will be. In this method, the distance between the outer corner of the eye and the mandibular angle, between the tragus and the outer corner of the mouth, and between the tragus and the soft tissue of the pogunion is measured in millimeters. Then the average of these three numbers is calculated and inflation is obtained.;Trismus. Timepoint: 2 and 7 days after surgery. Method of measurement: A ruler will be used to check for trismus before surgery, 2 and 7 days after. The distances between the upper and lower centers before and after the operation are measured using a ruler.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Karimi

Shahre-kord University of Medical Sciences

a2022karimi@gmail.com+98 31 3372 4342

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026