Evaluation of the effect of X-ray in CBCT imaging on the rate of nuclear changes and Repair Index of buccal mucosal cells

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220418054582N1

Enrollment

Registered

2022-05-30

Start date

2022-05-22

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention group: X-ray exposure.

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Adults 18 to 45 years old who have come to the university for a CBCT scan.

Exclusion criteria

Exclusion criteria: Perform radiotherapy in the last 28 days Smoking and mouthwash containing alcohol Existence of systemic disease Taking effective drugs in the oral mucosa

Design outcomes

Primary

Measure	Time frame
The extent of micronucleus changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Observation with a light microscope.;The extent of Karyorrhexis changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Observation with a light microscope.;The extent of Karyolysis changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Observation with a light microscope.;The extent of Broken egg changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Observation with a light microscope.;The extent of Repair Index changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Calculate according to the formula.	—

Measure

Time frame

The extent of micronucleus changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Observation with a light microscope.;The extent of Karyorrhexis changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Observation with a light microscope.;The extent of Karyolysis changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Observation with a light microscope.;The extent of Broken egg changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Observation with a light microscope.;The extent of Repair Index changes after X-ray exposure in CBCT imaging. Timepoint: At the beginning of the study (before exposure) and 10 days after exposure. Method of measurement: Calculate according to the formula.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactParissa Shahmohammadi

Islamic Azad University

parissashahmohammadi91@gmail.com+98 21 2256 4571

Outcome results