Comparison of the effectiveness of LASER with Aphtogel in the treatment of aphthous ulcers of the oral mucosa

Comparison of the effectiveness of 810 nm Diode LASER with Aphtogel mucoadhesive in the treatment of minor aphthous ulcers of oral mucosa (changes in diameter and pain of aphthous ulcers) in patients with minor aphthous ulcers

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220411054501N1

Enrollment

Registered

2022-04-25

Start date

2022-04-29

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Minor aphthous ulcer of the oral mucosa.

Interventions

Intervention 1: Intervention group: Patients in this group will be exposed to Diode LASER (elexion) with a wavelength of 810 nm and a power of 0.5 watts in continuous mode with a fiber diameter of 320

Eligibility

Sex/Gender

All

Age

10 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients referred to the clinic of Zanjan Dental School who have minor aphthous ulcers of the oral mucosa. Patients should be 10 to 80 years old. Complete the informed consent form by the patient

Exclusion criteria

Exclusion criteria: Being a smoker Having a systemic disease predisposing to aphthous ulcers

Design outcomes

Primary

Measure	Time frame
The rate of pest diameter changes in the two intervention groups. Timepoint: Measuring the pest diameter on the first, second and third days. Method of measurement: Dental gauge.;The amount of spontaneous pain in the two intervention groups. Timepoint: Measuring the amount of spontaneous pain on the first, second and third days. Method of measurement: VAS diagram describing the amount of pain.;The amount of functional pain in the two intervention groups. Timepoint: Measurement of the amount of functional pain in the first, second and third days of lesion. Method of measurement: VAS diagram describing the amount of pain.	—

Measure

Time frame

The rate of pest diameter changes in the two intervention groups. Timepoint: Measuring the pest diameter on the first, second and third days. Method of measurement: Dental gauge.;The amount of spontaneous pain in the two intervention groups. Timepoint: Measuring the amount of spontaneous pain on the first, second and third days. Method of measurement: VAS diagram describing the amount of pain.;The amount of functional pain in the two intervention groups. Timepoint: Measurement of the amount of functional pain in the first, second and third days of lesion. Method of measurement: VAS diagram describing the amount of pain.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRobab Noormohammadi

Zanjan University of Medical Sciences

dr.noormohammadi@zums.ac.ir+98 24 3336 5508

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026