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The effect of Aspirin in preventing preeclampsia

Comparison of the effect of Aspirin at a dose of 160 mg per day with the usual dose of Aspirin (80 mg daily) in the prevention of preeclampsia in high-risk pregnant women

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220410054469N1
Enrollment
216
Registered
2022-05-14
Start date
2022-06-22
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-eclampsia. Pre-eclampsia

Interventions

Intervention 1: Intervention group 1: Pregnant women in the 12-20 weeks of pregnancy who are at high risk of preeclampsia are treated with aspirin at a dose of 160 mg daily for 36 weeks. Aspirin table

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Pregnant women at 12-20 weeks of gestation at high risk for Preeclampsia.

Exclusion criteria

Exclusion criteria: Patients who find it difficult to follow a regular pattern of medication. Patients with heart, liver, thyroid, peptic ulcer diseases and bleeding disorder. Patients with a history of asthma, aspirin sensitivity, and the presence of major fetal disorders.

Design outcomes

Primary

MeasureTime frame
Incidence of Preeclampsia. Timepoint: From 12-20 to 36 weeks of pregnancy. Method of measurement: Mercury sphygmomanometer / laboratory abnormalities (including doubling of liver enzymes, doubling of serum creatinine and drop in platelets below 100,000).

Secondary

MeasureTime frame
Type of delivery (cesarean section or vaginal). Timepoint: Time of delivery. Method of measurement: Based on medical file and disease progression.;Term or preterm delivery. Timepoint: Time of pregnancy termination. Method of measurement: Based on medical file and disease progression.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParia Panahinia

Shahid Beheshti University of Medical Sciences

drpanahinia@yahoo.com+98 21 5506 2628

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026