The effect of HIIT on endothelial function in PCOS

Comparative study of the effect of 8 weeks high intensity interval training (HIIT) and moderate intensity aerobic training (MICT) on vascular endothelial factors and electrocardiogram data in women with polycystic ovary syndrome

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220404054405N1

Enrollment

Registered

2022-04-24

Start date

2022-04-09

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polytheistic ovary syndrome (PCOS). Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group 1: High Intensity Interval Training (HIIT) for 8 weeks (3 sessions a week). Intervention 2: Intervention group 2: Moderate Intensity Continious Training (MICT) for 8

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: PCOS diagnosis by endocrinologist Age range between 18 and 40 years BMI between 27 and 35

Exclusion criteria

Exclusion criteria: Having no history of chronic diseases like cardiac, diabetes, leaver, renal, or respiratory diseases Smoking or using alcohol Using orlistat, anti androgen, glococorticoids, and other drugs affecting on endothelial function

Design outcomes

Secondary

Measure	Time frame
Body weight. Timepoint: Before and after 8 weeks intervention. Method of measurement: Scale.;Lipid profile. Timepoint: Before and after 8 weeks intervention. Method of measurement: Medical laboratory.;FBS. Timepoint: Before and after 8 weeks intervention. Method of measurement: Medical laboratory.;Insulin. Timepoint: Before and after 8 weeks intervention. Method of measurement: Medical laboratory.	—

Measure

Time frame

Body weight. Timepoint: Before and after 8 weeks intervention. Method of measurement: Scale.;Lipid profile. Timepoint: Before and after 8 weeks intervention. Method of measurement: Medical laboratory.;FBS. Timepoint: Before and after 8 weeks intervention. Method of measurement: Medical laboratory.;Insulin. Timepoint: Before and after 8 weeks intervention. Method of measurement: Medical laboratory.

—

Primary

Measure	Time frame
Serum levels of VCAM-1. Timepoint: Before and after 8 weeks intervention. Method of measurement: Eliza kit.;Serum levels of E-selectin. Timepoint: Before and after 8 weeks intervention. Method of measurement: Eliza kit.;P dispersion. Timepoint: Before and after 8 weeks intervention. Method of measurement: ECG.;QT dispersion. Timepoint: Before and after 8 weeks intervention. Method of measurement: ECG.	—

Measure

Time frame

Serum levels of VCAM-1. Timepoint: Before and after 8 weeks intervention. Method of measurement: Eliza kit.;Serum levels of E-selectin. Timepoint: Before and after 8 weeks intervention. Method of measurement: Eliza kit.;P dispersion. Timepoint: Before and after 8 weeks intervention. Method of measurement: ECG.;QT dispersion. Timepoint: Before and after 8 weeks intervention. Method of measurement: ECG.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoya Hosseini

Royan Institute

rohosseini@yahoo.com+98 21 2356 2000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026