??Effect of two method surfactant administration on preterm neonates with respiratory distress syndrome

Comparison the effect of two method surfactant administration: Minimally invasive surfactant therapy)MIST) versus InSurE (Intubation, surfactant administration and extubation) in preterm neonates with respiratory distress syndrome: A randomized controlled trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220401054389N1

Enrollment

180

Registered

2022-05-24

Start date

2022-04-21

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

respiratory distress syndrome. Respiratory distress syndrome of newborn

Interventions

Intervention 1: Intervention group: Minimally invasive surfactant therapy(MIST). Intervention 2: Control group: Intubation (INSURE (Intubation, surfactant administration and extubation)).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Preterm neonates of 26 to 34 weeks with respiratory distress syndrome

Exclusion criteria

Exclusion criteria: Preterm neonates of 26 to 34 weeks with respiratory distress syndrome

Design outcomes

Primary

Measure	Time frame
Duration of oxygen therapy. Timepoint: Duration of hospitalization. Method of measurement: Number of hours of oxygen therapy after surfactant administration.	—

Secondary

Measure	Time frame
Duration of need for respiratory support. Timepoint: During and after the administration of surfactant until discontinuation of respiratory support. Method of measurement: Number of hours of need for respiratory support.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Behmadi

Mashhad University of Medical Sciences

behmadim4001@mums.ac.ir0098518400001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026