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Investigating the effect of cyproheptadine in chronic kidney patients

Investigating the effect of cyproheptadine on appetite ,laboratory and enteropometric indices in chronic renal failure pateint on hemodialysis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220329054368N2
Enrollment
124
Registered
2023-04-17
Start date
2023-05-21
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney patients undergoing hemodialysis. Chronic kidney disease, stage 5

Interventions

Intervention 1: Intervention group: Administration of cyproheptadine 4mg daily. Intervention 2: Control group: Placebo administration.

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Chronic kidney patients undergoing dialysis between 18 and 80 years of age, at least three months have passed since the start of dialysis. Patients who undergo dialysis twice a week with good efficacy. People's willingness to participate in the project. Absence of accompanying disease (infection, uncompensated heart failure, malignancy, liver cirrhosis, covid-19) that causes the patient's anorexia. Not taking drugs such as tricyclic antidepressants and corticosteroids that increase appetite.

Exclusion criteria

Exclusion criteria: Patient migration or death Dissatisfaction with the continuation of treatment by the patient. If other infectious or chronic diseases occur during the research period. Patients who underwent organ transplant surgery.

Design outcomes

Primary

MeasureTime frame
Appetite. Timepoint: Before and three months after the intervention. Method of measurement: NMA questionnaire.;Anthropometric indicators. Timepoint: Before and three months after the intervention. Method of measurement: Meter.;Laboratory indicators. Timepoint: Before and three months after the intervention. Method of measurement: cycmax.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnaz sadat Javanmardi

Yasouj University of Medical Sciences

farnaz.javanmardi@yums.ac.ir+98 71 3229 8671

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026