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The effectiveness of probiotics on asthmatic patients

The effectiveness of two types of probiotics (lactobacillusRhamnosus and Lactobacillus Reuteri ) on the pulmonary function test of moderate asthmatic patients aged 10 – 18 years.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220329054368N1
Enrollment
120
Registered
2022-05-21
Start date
2022-06-22
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma. Mild persistent asthma

Interventions

Intervention 1: Intervention group 1: Lactobacillus rhamnosus probiotic group. The amount of 10 drops of this probiotic will be given daily and orally with the dropper. Intervention 2: Intervention gr

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 18 Years

Inclusion criteria

Inclusion criteria: Patients between 10 - 18 years A well-known case of persistent moderate asthma that has just been diagnosed and, has a medical record and approval from an asthma and allergy specialist. All patients are taking fluticasone spray. Have no history of other respiratory illnesses including interstitial pneumonia, cystic fibrosis, sickle cell disease, and primary ciliary dyskinesia

Exclusion criteria

Exclusion criteria: Immigration or death of the patient. Patient dissatisfaction in continuing the treatment. In case of other infectious or chronic diseases during the research period.

Design outcomes

Primary

MeasureTime frame
Degree of asthma control, interleukin 13, blood eosinophil percentage, forced expiratory volume, peak expiratory flow, forced vital capacity. Timepoint: At the beginning of the study and two months after the intervention. Method of measurement: Asthma control test(ACT), spirometry, CBC diff, IL13 human kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnaz Sadat Javanmardi

Yasouj University of Medical Sciences

farnaz.javanmardi@yums.ac.ir+98 71 3229 8671

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026