functional dyspepsia. Functional dyspepsia
Conditions
Interventions
Intervention 1: Intervention group: In the first intervention group, 20 mg duloxetine (Cymbalta brand name) is prescribed for patients. Patients are advised to take the medicine with food. Patients sh
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: All patients with functional dyspepsia based on ROME-IV Having a diploma education Willingness to cooperate in the project Not having an allergy to Deloxetine and Nortriptyline
Exclusion criteria
Exclusion criteria: Having any type of serious psychiatric illness (severe anxiety or depression, psychosis, bipolar disorder, anorexia or bulimia nervosa) Having any other gastrointestinal disease except functional dyspepsia Taking antidepressants or antipsychotics in the last 6 weeks Failure to complete the questionnaires Non-cooperation in follow-ups causing severe side effects of the drug used (Deloxetine or Nortriptyline) Pregnancy or breastfeeding during the study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety. Timepoint: Measuring anxiety before the start of the study and one, two and three months after the start of the intervention. Method of measurement: Hamilton anxiety questionnaire.;Depression. Timepoint: Measuring depression before the start of the study and one, two and three months after the start of the intervention. Method of measurement: Hamilton depression questionnaire.;Quality of life. Timepoint: Measuring quality of life before the start of the study and one, two and three months after the start of the intervention. Method of measurement: Nippen questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahsa Mofateolshia
Shahid Beheshti University of Medical Sciences
Outcome results
None listed