nephrotoxicity.
Conditions
Interventions
Intervention 1: Intervention group:Patients are treated with vancomycin and theophylline. Vancomycin is prescribed at a dose of 15 mg/kg every eight hours from the first day of hospitalization. The du
Sponsors
Sabzevar University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Months to 18 Years
Inclusion criteria
Inclusion criteria: Patients with systemic infection treated with vancomycin Patients one month to 18 years Complete the informed consent form
Exclusion criteria
Exclusion criteria: Patients who are discharged from the hospital before three days. Patients with unpredictable complications. Patients with drug side effects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of people treated with vancomycin who develop microalbuminuria. Timepoint: Measurement of microalbuminuria at the beginning of the study and 72 hours after starting treatment with vancomycin. Method of measurement: Measurement of microalbuminuria in urine sample.The range is 30-300 mg per 24 hours.;The percentage of people treated with vancomycin who experience an increase in urea and creatinineCommunity Verified icon. Timepoint: Measurement of urea and creatinine at the beginning of the study and 72 hours after starting vancomycin treatment. Method of measurement: Measurement of urea and creatinine in serum samples.Depending on the patients age, urea 20-30 mg/dL and creatinine 0.4-1 mg/dL. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient weight change. Timepoint: before treatment & after three days from the start of treatment. Method of measurement: Measuring the patient's weight in kilograms with a digital scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAghil Keykhosravi
Sabzevar University of Medical Sciences
Outcome results
None listed