Nasolabial fold aging.
Conditions
Interventions
Intervention 1: Intervention group 1: Intervention Group 1: Injection of 2 ce stromal vascular fraction (SVF) cells extracted from abdominal fat into one side of the nasolabial area. Fat harvesting in
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age between 30 and 55 years Presence of moderate to severe nasolabial folds Willingness and written informed consent to participate Ability to attend treatment sessions and follow-up visits
Exclusion criteria
Exclusion criteria: Active inflammation or infection, including herpetic infection, at the injection site History of collagen vascular diseases Use of corticosteroids, immunosuppressive agents, or anticoagulant medications Platelet function disorders or thrombocytopenia Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of the nasolabial wrinkle. Timepoint: 1 and 3 months after the treatment. Method of measurement: Assessment of nasolabial wrinkle severity using the Global Aesthetic Improvement Scale (GAIS) by the physician. | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment complications. Timepoint: One and three months after the treatment. Method of measurement: Using a checklist containing treatment complications including pain, erythema and edema. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMasoumeh Roohaninasab
Iran University of Medical Sciences
Outcome results
None listed