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Comparison of the effect of 0.5, 2.5 and 5 mg doses of oral minoxidil in the treatment of female pattern of hereditary hormonal hair loss

Comparison of efficacy of 0.5, 2.5 and 5 mg oral minoxidil doses in the treatment of female pattern hair loss

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220322054341N1
Enrollment
60
Registered
2022-04-14
Start date
2022-04-21
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female pattern androgenic alopecia. Androgenic alopecia

Interventions

Intervention 1: Intervention group A: half a milligram of oral minoxidil daily for 6 months. Intervention 2: Intervention group B: two and a half milligrams of oral minoxidil daily for 6 months. Inter

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with clinical diagnosis of female pattern hair loss Sinclair scale one to four Age range 18 to 50 years old Conscious consent to enter the study and the possibility of attending visits and follow-up sessions

Exclusion criteria

Exclusion criteria: Patients taking medication other than vitamins or minerals for alopecia Pregnancy or breastfeeding Patients with serious internal disease, especially heart disease or comorbidities at the treatment site Psychiatric patients Abnormal tests at baseline

Design outcomes

Primary

MeasureTime frame
Improvement rate. Timepoint: 3 and 6 months after starting treatment. Method of measurement: By sinclair scale, clinical and dermatoscopic images (Determine the number and thickness of hair shafts per square centimeter).

Secondary

MeasureTime frame
Safety. Timepoint: 3 and 6 months after starting treatment. Method of measurement: Asking the patient about the side effects of treatment.;Tolerability. Timepoint: 3 and 6 months after starting treatment. Method of measurement: With Investigator Assessment of Tolerability scale (zero, low, medium and high or sufficient).;Patient satisfaction. Timepoint: 3 and 6 months after starting treatment. Method of measurement: With Caregiver treatment satisfaction (CTS) questionnaire (completely satisfied, satisfied, neither satisfied nor dissatisfied, dissatisfied and completely dissatisfied).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Roohaninasab

Iran University of Medical Sciences

rohaninasab.m@iums.ac.ir+98 21 6435 2421

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026