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The effect of prp on oligospermia

Evaluate the effect of platelet-rich plasma(PRP) by testicular injection on sperm DNA fragmentation index of infertile men with sever oligoasthenoteratozoospermia (OAT)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220317054318N4
Enrollment
160
Registered
2023-07-05
Start date
2023-07-23
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oligostenoteratozoospermia. Oligospermia

Interventions

Intervention 1: Intervention group: Includes sample subjects receiving platelet-rich plasma via intratesticular injection. Intervention 2: Control group: Sample subjects receiving routine treatment.

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
25 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age range 20-45 years Sperm count <20 million Movement less than 106 x 5 ml, progressive movement < 20%, normal morphology < 10% Not receiving other treatments such as hormone therapy Not suffering from underlying diseases (such as diabetes, kidney disease, liver disease, drug and alcohol addiction) and types of cancer and receiving chemotherapy treatments Absence of signs of infection in semen Untreated varicocele

Exclusion criteria

Exclusion criteria: Unwillingness to continue participating in the study

Design outcomes

Primary

MeasureTime frame
Sperm DNA fragmentation index. Timepoint: Before the start of the intervention and after 3 months from the time of PRP injection. Method of measurement: Sperm DNA breakage index test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShamim pilehvari

Hamedan University of Medical Sciences

Sh.pilehvari@yahoo.com+98 81 3131 4058

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026