Investigating the effect of PRP in oligospermia

Evaluate the effect of platelet-rich plasma(PRP) by testicular injection on spermogram parameters of infertile men with sever oligoasthenoteratozoospermia (OAT)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220317054318N2

Enrollment

Registered

2023-02-08

Start date

2023-02-20

Completion date

Unknown

Last updated

2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oligostenoteratozoospermia. Male infertility

Interventions

Intervention 1: Intervention group:including 44 patients who were injected with 2cc of platelet-rich plasma by the urologist inside their testicles. Intervention 2: Control group:44 patients who do no

Eligibility

Sex/Gender

Male

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age range 20-45 years. sperm count less than 20 million, Movement less than 106 x 5 ml, progressive movement < 20%, normal morphology < 10%

Exclusion criteria

Exclusion criteria: Receiving other treatments for oligospermia such as hormone therapy Suffering from underlying diseases (such as diabetes, kidney disease, liver disease, drug and alcohol addiction) and types of cancer and receiving chemotherapy treatments

Design outcomes

Primary

Measure	Time frame
Sperm count and motility in men. Timepoint: 3 months after intratesticular platelet rich plasma injection. Method of measurement: Sperm analysis, DNA fragmentation index.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSHamim Pilehvary

Hamedan University of Medical Sciences

Sh.pilevar@umsha.ac.ir+98 81 3834 0266

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 5, 2026