Comparison of the effect of dorsolateral prefrontal cortex stimulation and correction of asymmetry in alpha waves in depressive disorder

Comparison of the effectiveness of dorsolateral prefrontal cortex transcranial direct current stimulation and modification of frontal alpha asymmetry in the prefrontal region on patients with major depressive disorder

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220316054306N1

Enrollment

Registered

2022-04-04

Start date

2022-04-09

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder. Major depressive disorder, single episode

Interventions

Intervention 1: Intervention group 1: Neurofeedback protocol will include 15 sessions of 20 minutes (3 sessions per week) in the form of increasing beta waves in the range of 18-15 Hz and decreasing a

The anode electrode will be on the F3 region and the cathode electrode will be on the F4.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age above 18 years Do not have any neurological disorders Absence of psychotic disorders Has not been on any medication or psychological treatment for up to 1 month before the start of the sessions Be right hand Having depressive disorder based on a semi-structured interview

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Depression score in Beck Depression Inventory. Timepoint: Before the study, in sessions 5, 10, 15 and three months after the last session. Method of measurement: Using Beck Depression Inventory.;Negetive and positive affects based on scores on positive and negative affect schedule. Timepoint: Before the study, in sessions 5, 10, 15 and three months after the last session. Method of measurement: Positive and Negative Affect Schedule.;Fatigue based on multidimensional fatigue inventory. Timepoint: Before the study, in sessions 5, 10, 15 and three months after the last session. Method of measurement: Multidimensional Fatigue Inventory.	—

Measure

Time frame

Depression score in Beck Depression Inventory. Timepoint: Before the study, in sessions 5, 10, 15 and three months after the last session. Method of measurement: Using Beck Depression Inventory.;Negetive and positive affects based on scores on positive and negative affect schedule. Timepoint: Before the study, in sessions 5, 10, 15 and three months after the last session. Method of measurement: Positive and Negative Affect Schedule.;Fatigue based on multidimensional fatigue inventory. Timepoint: Before the study, in sessions 5, 10, 15 and three months after the last session. Method of measurement: Multidimensional Fatigue Inventory.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahab

Shahid Beheshti University of Medical Sciences

lotfiniashahab@sbmu.ac.ir+98 21 2243 9770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026