Non-alcoholic fatty liver disease. Non-alcoholic fatty liver disease
Conditions
Interventions
Intervention 1: Intervention group: Receive 500 mg Familact Capsules (Probiotic + Prebiotic) prepared from Zist Takhmir Company, once a day after meals for 8 weeks. Intervention 2: Control group: Rece
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: Children and adolescents 10 to 18 years of age with non-alcoholic fatty liver disease confirmed by ultrasound and ALT more than 1.5 to 5 times normal
Exclusion criteria
Exclusion criteria: Patients with alcoholic steatohepatitis Patients with systemic diseases (such as diabetes), inflammatory diseases, autoimmune diseases of the liver Positive serology of viral hepatitis Positive AMA ANA Positive Ceruloplasmin Children with hypothyroidism Taking nutritional supplements Other secondary causes of fatty liver Patients with any medication that affects the liver Liver enzyme levels are more than 6 times normal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver enzymes (ALT,AST). Timepoint: At the beginning of the study, 8 weeks after taking the drug. Method of measurement: blood test.;Lipid factors (cholesterol, LDL, HDL). Timepoint: At the beginning of the study, 8 weeks after taking the drug. Method of measurement: blood test.;Fatty liver grade. Timepoint: At the beginning of the study, 8 weeks after taking the drug. Method of measurement: Sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body mass index. Timepoint: At the beginning of the study, 8 weeks after taking the drug. Method of measurement: Meters to measure height and scales to measure weight.;Fasting blood sugar. Timepoint: At the beginning of the study, 8 weeks after taking the drug. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Naseri Taheri
Kashan University of Medical Sciences
Outcome results
None listed