Skip to content

A comparative study of CGRP neuropeptide levels in patients with endometriosis pain treated with dienogest

A comparative study of CGRP neuropeptide levels in patients with endometriosis pain treated with dienogest

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220313054264N1
Enrollment
10
Registered
2022-06-12
Start date
2022-04-03
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometriosis.

Interventions

Intervention group: Patients with endometriosis with pain, according to the doctor's diagnosis for drug treatment of pain Dinogen 2 mg per day orally (tablets) (Iran Hormone Company) once a day for 6

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women aged 18-44 years with pain and suspected endometriosis Do not take hormonal drugs containing estrogen or progesterone for three months No pregnancy Absence of genital or breast cancers No abnormal vaginal bleeding No breastfeeding for 3 months Do not use housing during the last week No surgery in the last 3 months No liver problems No strong history of venous thrombosis or embolism Body mass index 5 / 18-26

Exclusion criteria

Exclusion criteria: Has a history of any genital cancer in the pelvic area Hormone therapy for the past 3 months Suffering from a variety of systemic diseases History of endometrial destruction by thermal balloon or resectoscope

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: 3 months and 6 months later. Method of measurement: Vas score questionnaire.;The amount of CGRP neuropeptide. Timepoint: 6 months later. Method of measurement: ELISA device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarziyeh Ajdary-Iran University of Medical Sciences

Iran University of Medical Sciences

ajdari.m@iums.ac.ir+98 21 6435 2562

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026