effect of adding Dexamethasone and Dexmedetomidine to Bupivacaine infiltration

Comparison of the effect of adding Dexamethasone and Dexmedetomidine to Bupivacaine infiltration on cleft lip surgery pain

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220312054261N1

Enrollment

Registered

2022-04-03

Start date

2022-05-22

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the pain. Other chronic pain

Interventions

Intervention 1: Intervention group: epinephrine 1200000, 1 cc bupivacaine 0.5% and 0.1 mg / kg dexamethasone with a total volume of 2 cc- Drops of dexamethasone ampoules 8 mg / 2 ml [Raha Pharmacy]-

Eligibility

Sex/Gender

All

Age

3 Months to 10 Months

Inclusion criteria

Inclusion criteria: Age between 3 and 10 months Candidate of unilateral cleft lip of both sexes The first operation is lip cleft Duration of surgery less than 2 hours ASA patients have I and II Parents must complete the study entry consent form.

Exclusion criteria

Exclusion criteria: The surgery lasts more than 2 hours Hemodynamic changes require therapeutic action Re-need for topical injection of epinephrine at the site of surgery Reaction to any of the drugs studied

Design outcomes

Primary

Measure	Time frame
Need to Tranquilizer. Timepoint: Preoperative, postoperative, 24 hours postoperative. Method of measurement: Using the scale of face, legs, activity, crying and comfort, which is one of the most common and widely used scales of observational-behavioral pain.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSedighe Shahhosseini

Esfahan University of Medical Sciences

nasrin20ir@gmail.com003133866266

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026