Evaluation and comparison of two methods of expectant management and drug treatment with oral contraceptive pills

Evaluation and comparison of two methods of expectant management and drug treatment with oral contraceptive pills in the elimination of pregnancy remnants due to incomplete spontaneous abortion in the first trimester of pregnancy - randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220307054209N1

Enrollment

170

Registered

2022-08-01

Start date

2022-06-10

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disposal of pregnancy remnants due to incomplete spontaneous abortion. Spontaneous abortion

Interventions

Intervention 1: The first intervention group: expectant management is performed for three weeks. Intervention 2: Intervention group: medical treatment is performed using OCP oral contraceptive pills

Eligibility

Sex/Gender

Female

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women 15 to 45 years old Women who had a miscarriage in the first trimester (less than 12 weeks) Women who have had an incomplete abortion and a trans-vaginal ultrasound confirm the presence of pregnancy debris below 4 cm. Women whose pregnancy miscarriage has been confirmed (less than 4 cm) and has been the result of a failed intrauterine pregnancy. Patients with stable vital signs Patients asymptomatic or with spotting and mild vaginal bleeding.

Exclusion criteria

Exclusion criteria: Patients with unstable vital signs Patients with suspected molar pregnancy Patients with contraindications to OCP

Design outcomes

Primary

Measure	Time frame
Disposal of pregnancy remnants due to spontaneous abortion. Timepoint: 21 days after intervention. Method of measurement: By checklist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Rahimi

Iran University of Medical Sciences

Mrahimi.gynecologist@gmail.com+98 21 86701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026