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The effect of gapentin cream on pruritus in dialysis patients

Evaluation of the effect of gabapentin topical cream in improving itching of end-stage renal disease to dialysis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220306054206N1
Enrollment
80
Registered
2022-03-17
Start date
2022-05-20
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Itching end-stage renal disease leading to dialysis. Pruritus

Interventions

Intervention 1: Intervention group: Gabapentin will be dissolved in the liquid phase, and finally 5% gabapentin cream will be prepared in water-based cold cream type oil. It is used once a day for 4 w

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Target community patients with pruritus ani. The itching studied in this study should be itching of the whole body except the head, face and neck.

Exclusion criteria

Exclusion criteria: Itching of the head, neck and face Other simultaneous skin diseases on the trunk and limbs

Design outcomes

Primary

MeasureTime frame
Determining the effectiveness of gabapentin topical cream in improving itching in dialysis patients. Timepoint: Patients receive medication for 4 weeks and are followed up for 4 weeks thereafter. Method of measurement: Two questionnaires are used to score patients' pruritus: 12-item and 5-item.

Secondary

MeasureTime frame
Determining the mean changes in pruritus score before and after application of Gabapentin topical cream according to age and sex, duration of dialysis initiation and underlying cause of dialysis. Timepoint: Patients receive medication for 4 weeks and are followed up for 4 weeks thereafter. Method of measurement: By two questionnaires: 12-item and 5-item.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Mohamadian

Esfahan University of Medical Sciences

parisa.m@edu.mui.ac.ir+98 31 3444 8056

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026