loss of consciousness.
Conditions
Interventions
Intervention 1: Intervention group: Methylphenidate is given orally at a dose of 20 mg twice a day for 48 hours. Intervention 2: Control group: Receive standard treatment of loss of consciousness with
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age 18 years and above Informed consent of the legal guardian of the patient to participate in the study Having decreased consciousness due to poisoning (GCS 13 and below) Having the ability to move to measure the movement
Exclusion criteria
Exclusion criteria: History of allergy to methylphenidate Po intolerance Unstable vital signs Pregnancy and lactation in female patients Receiving a specific antidote (example: Flumazenin, Naloxone, etc.) Having mental retardation, blindness, deafness Having a history of brain damage, high blood pressure, ischemic heart disease Having epilepsy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The state of consciousness of patients after receiving methylphenidate. Timepoint: 12, 24, 36 and 48 hours after receiving the Methylphenidate. Method of measurement: Glasgow Coma Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| The score obtained from the Reed Scaling criterion. Timepoint: 12, 24, 36, and 48 hours after receiving methylphenidate. Method of measurement: Levels 1 to 4 are obtained by examining blood pressure-respiratory-reflexes and pain response. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMitra Rahimi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed