Investigating the effect of curcumin on the levels of liver enzymes in opium poisoning

Investigating the effect of curcumin consumption on liver enzyme levels in opium-poisoned patients hospitalized in the Poisoned ICU department

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220305054196N2

Enrollment

Registered

2023-04-09

Start date

2023-03-20

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Poisoning by opium. Poisoning by opium, undetermined

Interventions

Intervention 1: Intervention group: Curcumin supplement gavage, dose 1500 mg daily for 7 days, Dineh Pharmaceutical Company. Intervention 2: Control group: Normal saline gavage, with the rate of 1500

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Opium poisoning Referred to the emergency department of Loghman Hospital in Tehran admitted to the intensive care unit

Exclusion criteria

Exclusion criteria: Concomitant poisoning with other drugs Lack of consent of companions to participate in the study death of the patient

Design outcomes

Primary

Measure	Time frame
Liver enzyme levels. Timepoint: Before treatment and daily up to 7 days after treatment. Method of measurement: Blood sampling is done and the level of liver enzymes is determined using a laboratory kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMitra Rahimi

Shahid Beheshti University of Medical Sciences

mrahimi744@gmail.com+98 21 5541 9005

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026