Non-addicted patients with methadone poisoning. Poisoning by, adverse effect of and underdosing of methadone
Conditions
Interventions
Intervention 1: Intervention group 1: Non-addicted patients with methadone poisoning alone who are over 18 years old, have not been treated with methadone maintenance and naloxone reduction by naloxon
Sponsors
Toxicological Research Center
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with methadone toxicity Age over 18 years
Exclusion criteria
Exclusion criteria: Opioid addiction Concomitant poisoning with methadone and other drugs, especially sedatives Patients who do not need Naloxone treatment Patients with heart failure patients with renal failure patients being treated with Methadone Maintenance Treatment method
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of consciousness level during tapering of Naloxone. Timepoint: Initiate treatment and then assess the patient's consciousness every 3 hours. Method of measurement: Using the Glasgow Coma Scale (GCS).;Respiratory depression of the patient during reducing the dose of naloxone every 3 hours. Timepoint: Assess the patient's condition every 1 hours. Method of measurement: Based on respiration rate per minute. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMitra Rahimi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed