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Comparison of effect of ketamine and lidocaine on prevention of emergence agitation in Rhinoplasty

Comparison of effect of ketamine and lidocaine on prevention of emergence agitation in Rhinoplasty

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220302054164N1
Enrollment
72
Registered
2022-04-06
Start date
2022-04-04
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rhinoplasty surgery. Intraoperative and postprocedural complications and disorders of the respiratory system, not elsewhere classified

Interventions

Intervention 1: Intervention group: Intervention group: Lidocaine group: 1.5 mg / kg lidocaine intravenously 20 minutes before surgery completion. Intervention 2: Intervention group: Intervention grou

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Referral for elective rhinoplasty surgery Age 18-45 years Lack of known allergies to the drugs used in the present study No pregnancy No drug addiction Do not use psychotropic drugs Perform surgery under general anesthesia Classification of ASA class, I-II

Exclusion criteria

Exclusion criteria: Taking painkillers and sedatives 24 hours before surgery History of heart disease, nervous system, and neurological disorders Patient with a history of previous rhinoplasty History of seizures Duration of anesthesia and surgery more than 2 hours

Design outcomes

Primary

MeasureTime frame
Restlessness when waking up from anesthesia. Timepoint: During anesthesia until the end of the patient's presence in the recovery room, the patient's vital signs will be measured. Also, during the presence at recovery, the RASS and NRS questionnaires will be filled in. Method of measurement: After extubation and transfer of the patient to recovery room, the patient's restlessness will be recorded by the RASS scale every 10 minutes until discharge from the recovery by a trained nurse who does not know the patient group. Also, after transferring the patient to recovery room, the amount of postoperative pain will be recorded by the Numerical Pain Measurement Scale (NRS) every 10 minutes.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSafoora Omidvar

Arak University of Medical Sciences

s_omidvar1991@yahoo.com+98 71 5335 2678

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026