Covid-19. COVID-19
Conditions
Interventions
Intervention 1: Intervention group: Injection of vitamin C (Caspian Company) in amount of 1.5 gr for each patient in the intervention group is performed as an intravenous infusion using normal saline
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adults (age 18 years or older) SPO2<92% Being treated in the ward Positive PCR test Involvement of Chest-CT-Scan
Exclusion criteria
Exclusion criteria: Patients with a history of allergy to vitamin C Patients with dyspnea caused by cardiogenic pulmonary edema Pregnant women Lactating women Patients with a previous history of end-stage pulmonary disease, end-stage malignant tumor, diabetic ketoacidosis, severe kidney Active kidney stone disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| White Blood Cell including neutrophil and lymphocyte. Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with X1000/mm3.;Inflammatory factor(Erythrocyte Sedimentation Rate)/ESR. Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with mm/h.;Inflammatory factor (C-Reactive Protein)/CRP. Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with Diagnostic Kit Unite /liter.;Alkaline Phosphatase(Enzyme in liver and bones)/ALK-P. Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with Diagnostic Kit Unite /liter.;Aspartate aminotransferase(Liver enzyme)/AST. Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with Diagnostic Kit Unite /liter.;Alanine aminotransferase(Liver enzyme)/ALT. Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with Diagnostic Kit Unite /liter.;Lactate dehydrogenase(Enzyme in heart and Red blood cell)/LDH. Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with Diagnostic Kit Unite /liter.;Blood coagulation factor(D-dimer). Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with Diagnostic Kit Unite /liter.;Blood coagulation factor(Prothrombin Time)/PT. Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with Diagnostic Kit Unite /liter.;Blood coagulation factor(Partial Thromboplastin Time)/PTT. Timepoint: Before the intervention and 5 days after. Method of measurement: Measure with blood test and scale with Diagnostic Kit Unite /liter.;Blood coagulation factor(International Normalized Ratio)/INR. Timepoint: Before the interventio | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospitalization. Timepoint: Day of arrival until discharge from the hospital. Method of measurement: Patient record.;Death. Timepoint: Day of arrival until discharge from the hospital or death. Method of measurement: Patient record. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Malek
Oroumia University of Medical Sciences
Outcome results
None listed