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Evaluation of the effect of comparing bronchodilators with corticosteroids and bronchodilators in children with bronchiolitis

Evaluation of the effect of comparing bronchodilators with corticosteroids and bronchodilators in children with bronchiolitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220225054120N1
Enrollment
60
Registered
2022-05-11
Start date
2022-05-07
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiolitis. Influenza due to unidentified influenza virus with other respiratory manifestations

Interventions

Intervention group: The first group: hydrocortisone with Oxycort brand 5 mg per weight (one dose) and bronchodilator as ventolin or salbutamol at a dose of 0.15 mg per weight with an interval of 20 mi

Sponsors

Ilam University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Months to 24 Months

Inclusion criteria

Inclusion criteria: Inclusion criteria Based on the standard definition of bronchiolitis, the first or second episode of respiratory distress with wheezing and clinical evidence of viral respiratory infection such as body temperature 38 ° C and above, tachypnea and tachycardia or Coryza symptoms.

Exclusion criteria

Exclusion criteria: History of more than two episodes of respiratory distress in the past. Chronic heart and lung disease Immunodeficiency Down Syndrome Metabolic or neurological illness History of prematurity (less than 34 weeks of Gesteitional age) Use of mechanical ventilation in infancy Positive family history of utopia Ill child in need of hospitalization due to dehydration, decreased level of consciousness, lethargy or symptoms of respiratory failure

Design outcomes

Primary

MeasureTime frame
All infants 2 to 24 months of age with the first Wise attack who are diagnosed with bronchiolitis need to be hospitalized and receive oxygen. Timepoint: After initial evaluation (on arrival), second evaluation (1 hour appointment) (1 dose of hydrocortisone ampoule, 5 mg per kg body weight and ventolin nebulizer at a dose of 0.15 mg per kg body weight (minimum dose) 2.5 mg and a maximum of 5 mg) and continue ventilation every 20 minutes for up to 3 doses, including monitoring of oxygen prevalence (using pulse oximetry), respiration rate, and pulse rate. In addition to oxygen saturation, Pulse rate and respiration rate, RDA Score and Clinical Score will also be checked and recorded. Method of measurement: CBSS table.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Maleki

Ilam University of Medical Sciences

z.maleki69@yahoo.com+98 41 4444 2476

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026