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Evaluating the pain relieving effects of Non-Thermal CO2 Laser Therapy (NTCLT) on chemotherapy induced oral mucositis

Evaluating the pain relieving effects of Non-Thermal CO2 Laser Therapy (NTCLT) on chemotherapy induced oral mucositis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220220054073N1
Enrollment
20
Registered
2023-06-27
Start date
2015-04-21
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chemotherapy-induced oral mucositis. Oral mucositis (ulcerative) due to antineoplastic therapy

Interventions

Intervention group: Patients with chemotherapy-induced oral mucositis. In this before-after clinical trial, the patients were irradiated with a single session of NTCLT. At first, the surgical staff a
Lancet-2, Russia) beam (power: 1 Watt, in continuous mode) was irradiated through the gel layer. The lesion was scanned with rapid circular motion of the handpiece over the lesion, while the distance

Sponsors

Iran National Science Foundation (INSF)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Chemotherapy-induced oral mucositis with grade 1-4 according to the WHO classification index The minimum literacy to read and write and filling the forms Providing written informed consent after the physician's explanation about the treatment method

Exclusion criteria

Exclusion criteria: Pregnancy Breastfeeding History of Photo sensitivity or use of photo sensitizing drugs Head and neck radiotherapy Taking narcotic painkillers

Design outcomes

Primary

MeasureTime frame
Non-contact (Non-stimulate) pain score. Timepoint: before laser irradiation, immediately after laser irradiation, 4 hours, 8 hours after laser irradiation and then daily until the seventh day. Method of measurement: (Visual analogue scale) VAS.;Contact pain score. Timepoint: before laser irradiation, immediately after laser irradiation, 4 hours, 8 hours after laser irradiation and then daily until the seventh day. Method of measurement: (Visual analogue scale) VAS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Nasrin Zand

Iranian academic center for education culture and research

zand_nas@yahoo.com+98 21 6649 4649

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026