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The effects of active and passive mobilization of tibial nerve in neuropathy of type 2 diabetic patients

Comparing the effects of active and passive mobilization of tibial nerve on pain intensity and conduction velocity of tibial nerve in neuropathy of type 2 diabetic patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220216054035N2
Enrollment
30
Registered
2025-08-05
Start date
2025-09-03
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathy of diabetes. Type 2 diabetes mellitus with diabetic neuropathy, unspecified

Interventions

Intervention 1: Intervention group 1: Active mobilization of tibial nerve is performed five sessions per week for 3 weeks in supervised manner. To perform the neurodynamic gliding exercise of the tibi

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: Passing at least 2 years since the onset of diabetes Their leg pain is 3 or higher Their blood sugar levels are in the range of 100-250 It has been 6 months since the onset of neuropathy symptoms Men and women with type 2 diabetes In the age group of 40-75 years Grade 1 and 2 neuropathy via monofilament instrument, Michigan questionnaire, and tibial nerve conduction velocity assessment

Exclusion criteria

Exclusion criteria: Diabetic foot ulcer Irritable pain Lumbar disc herniation Damage to the nerves of the lower extremities History of cardiovascular disease Musculoskeletal deformity Lack of cooperation or understanding during sensory testing or manual therapy Dependency to drug or alcohol Lumbar disc herniation Damage to the nerves of the lower extremities Retinopathy History of cardiovascular disease

Design outcomes

Primary

MeasureTime frame
Conduction velocity of tibial nerve. Timepoint: Before intervention and end of treatment sessions (19th day). Method of measurement: Electromyography.;Pain. Timepoint: Before intervention and end of treatment sessions (19th day). Method of measurement: Visual analog scale (VAS).

Secondary

MeasureTime frame
Neuropathy score on the Michigan Questionnaire. Timepoint: Before intervention and end of treatment sessions (19th day). Method of measurement: With Michigan questionnaire, this questionnaire consists of two parts: Part A,ranging from 0 to a score of 13, with a higher score indicating greater severity of neuropathy , and Part B, where a score above 2 indicates neuropathy.;Quality of life questionnaire score. Timepoint: Before intervention and end of treatment sessions (19th day). Method of measurement: Quality of life Questionnaire with 15 questions.;Leg raising range of motion. Timepoint: Before intervention and end of treatment sessions (19th day). Method of measurement: Goniometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMonire Alem

Shahid Beheshti University of Medical Sciences

monireaalem@gmail.com+98 21 7754 2057

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026