A comparative study of recurrence rate and complications between mitomycin c, interferone alpha 2b and bevasizumab after primary pterygium surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220215054028N1

Enrollment

Registered

2022-05-17

Start date

2022-05-20

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary pterygium. Pterygium of eye

Interventions

Intervention 1: Intervention group: after pterygium removal, 1.25 mg bevacizumab is injected into the recipient conjunctiva 5 mm far from the free edge of the recipient area in the superior, inferior

Eligibility

Sex/Gender

All

Age

40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Existence of primary pterygium at least 1 mm in size Decrease in visual acuity due to pterygium The patient's tendency for pterygium surgery Having no history of previous pterygium surgery Having no history of allergy to interferone alpha 2 B Cylinder caused by pterygium

Exclusion criteria

Exclusion criteria: Patients with recurrent pterygium Patients with no tendency for pterygium surgery Patients with active ophthalmic infection

Design outcomes

Primary

Measure	Time frame
Pterygium recurrence rate after primary pterygium surgery. Timepoint: At the beginning of the study, after 48 hours, one week, one month, 6 months and then 1 year after the operation. Method of measurement: Slit lamp.;Complication rate after primary pterygium surgery. Timepoint: At the beginning of the study, after 48 hours, one week, one month, 6 months and then 1 year after the operation. Method of measurement: Slit lamp.	—

Measure

Time frame

Pterygium recurrence rate after primary pterygium surgery. Timepoint: At the beginning of the study, after 48 hours, one week, one month, 6 months and then 1 year after the operation. Method of measurement: Slit lamp.;Complication rate after primary pterygium surgery. Timepoint: At the beginning of the study, after 48 hours, one week, one month, 6 months and then 1 year after the operation. Method of measurement: Slit lamp.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSolmaz Momtahan ghalati

Mashhad University of Medical Sciences

momtahens981@mums.ac.ir+98 938 094 6737

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026