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Comparison of prophylactic effect of single-dose and continuous-dose antibiotics on urinary tract infections (UTI) following transurethral lithotripsy (TUL) and stenting

Comparison of prophylactic effect of single-dose and continuous-dose antibiotics on urinary tract infections (UTI) in patients with Double-J ureteral stent following transurethral lithotripsy (TUL)

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220213054009N1
Enrollment
90
Registered
2022-04-18
Start date
2022-05-21
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative urinary tract infection. Infection and inflammatory reaction due to urinary catheter

Interventions

Intervention 1: Intervention group: receiving single dose intravenous ciprofloxacin (400 mg) before procedure. Intervention 2: Control group:receiving single dose intravenous ciprofloxacin (400 mg) be

Sponsors

Urology Research Center, Guilan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Have a sterile urine culture before stent placement

Exclusion criteria

Exclusion criteria: Fever Use of antibiotics during the 2 weeks before the stenting operation Purulent discharge during TUL History or treatment of obstructive symptoms Chronic bacterial prostatitis Chronic pelvic pain syndrome Prostate cancer Chronic ureteral obstruction Obstruction due to malignancy Iatrogenic trauma Conditions prone to bleeding History of bladder cancer Recurrent urinary tract infections Irritable bladder syndrome History of mental or neurological disease Taking alpha-blockers and anticholinergics, painkillers, or other medications that may interfere with the symptoms of ureteral stent Pregnancy

Design outcomes

Primary

MeasureTime frame
Urinary tract infection after inserting the stent. Timepoint: The mean duration of stent indwelling time and before removing the stent. Method of measurement: Urine culture and urinalysis.;Fever. Timepoint: During the stent indwelling time. Method of measurement: Interview and physical exam.;Hematuria. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.;Dysuria. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.;Frequency. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.;Nocturia. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.;Flank pain. Timepoint: During of stent indwelling time and before removing the stent. Method of measurement: Interview and questionnaire.

Secondary

MeasureTime frame
Side effects of contentious antibiotics. Timepoint: During of stent indwelling time. Method of measurement: Interview.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahador Heidari Bateni

Rasht University of Medical Sciences

Bahador_hb@yahoo.com+98 13 3352 5259

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026