cerebral palsy
Conditions
Interventions
Intervention group: Vial toxin botulinum type A (massport) diluted with 3.2 cc of normal saline and depending on the patient's weight in each salivary gland 30 to 50 units (less than 15 kg 30 units, b
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
4 Years to 16 Years
Inclusion criteria
Inclusion criteria: patients with cerebral palsy Drooling frequency scale 4 and severity and Teacher scale more than 4 Age between 4 and 16 years Consent of parents or legal guardians to enter the study
Exclusion criteria
Exclusion criteria: Contraindications of botulinum toxin A injection such as myasthenia gravis and Eaton-Lambert syndrome Botulinum toxin A injection for at least the last four months Receiving systemic medication to treat sialorrhea in the last three months Recent maxillofacial surgery that may interfere with saliva production and flow.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Drooling frequency score based on Drooling frequency scale and Teacher drooling scale. Timepoint: Before intervention, 2 weeks, 1 month, 2 months, 4 months, 6 months and 9 months after botulinum toxin injection. Method of measurement: Drooling Frequency and Teacher drooling scale.;Drooling severity score based on Drooling severity scale and Teacher drooling scale. Timepoint: Before intervention, 2 weeks, 1 month, 2 months, 4 months, 6 months and 9 months after botulinum toxin injection. Method of measurement: Drooling Severity and Teacher drooling scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Javad Sayedi
Mashhad University of Medical Sciences
Outcome results
None listed