The effect of oral nutrition supplement (ONS) on autologous hematopoietic stem cell transplantation

The effect of oral nutrition supplement (ONS) on nutritional and clinical status of patients undergoing autologous hematopoietic stem cell transplantation

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220208053971N2

Enrollment

Registered

2022-12-09

Start date

2022-12-17

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Lymphoma. Condition 2: multiple myeloma. Non-Hodgkin lymphoma, unspecified Multiple myeloma

Interventions

Intervention 1: Intervention group: The type of intervention in the treatment group will be an oral nutritional supplement of 500 kcal, including carbohydrates, fat, protein, vitamins, and minerals. T

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with lymphoma or multiple myeloma are candidates for autologous hematopoietic stem cell transplantation Age range 18-50 years

Exclusion criteria

Exclusion criteria: Reluctance to cooperate

Design outcomes

Primary

Measure	Time frame
Weight. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Seca Scales.;Body mass index(BMI). Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Questionnaire and calculation.	—

Measure

Time frame

Weight. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Seca Scales.;Body mass index(BMI). Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Questionnaire and calculation.

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Secondary

Measure	Time frame
Appetite. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Visual analog scale.;Hand grip strength. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Hand dynamometer.;Mid-arm circumference. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Seca tape measure.;Calf circumference. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Seca tape measure.;Total energy intake. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Food record questionnaire & Analysis by N4 software.;Protein intake. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Food record questionnaire & Analysis by N4 software.;Carbohydrate intake. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: food record questionnaire & Analysis by N4 software.;Fat intake. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measuremen	—

Measure

Time frame

Appetite. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Visual analog scale.;Hand grip strength. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Hand dynamometer.;Mid-arm circumference. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Seca tape measure.;Calf circumference. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Seca tape measure.;Total energy intake. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Food record questionnaire & Analysis by N4 software.;Protein intake. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: Food record questionnaire & Analysis by N4 software.;Carbohydrate intake. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measurement: food record questionnaire & Analysis by N4 software.;Fat intake. Timepoint: The first stage, on the negative day 7 of transplantation, the second stage, positive 14 days after transplantation, and the third stage, 90 days after transplantation. Method of measuremen

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hamed Mohammadi

Tehran University of Medical Sciences

mohamadihd@gmail.com0098 21 889900285

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026