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The effect of Trachyspermum Ammi syrup on the prevention of ventilator-associated pneumonia

The effect of Trachyspermum Ammi syrup on the prevention of ventilator-associated pneumonia in mechanically ventilated patients in the trauma intensive care units

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220204053931N2
Enrollment
60
Registered
2022-05-11
Start date
2022-05-15
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator associated pneumonia. Influenza and pneumonia

Interventions

Intervention 1: Intervention group: Gavage of Trachyspermum Ammi syrup 10%, from the first day of enteral feeding, 10 ml, three times a day for ten days. Intervention 2: Control group: gavage of plac

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Having an oral endotracheal tube Receiving mechanical ventilation ICU hospitalization due to trauma

Exclusion criteria

Exclusion criteria: Having pneumonia at the time of admission Cardiopulmonary diseases Lung contusion Pulmonary thromboembolism Atelectasis Inflammatory diseases Digestive diseases Liver and biliary diseases History of allergies to herbal drugs Symptoms of pulmonary aspiration Weak immune system Substance abuse and addiction Extubation before 10 days Death or ICU discharge before 10 days Sudden change in hemodynamic status Complications such as hives, itching and skin rashes that can be a sign of allergy to Trachyspermum Ammi syrup

Design outcomes

Primary

MeasureTime frame
Ventilator-associated pneumonia. Timepoint: Ventilator-associated pneumonia will be assessed on the fifth and tenth day of the intervention. Method of measurement: Ventilator-associated pneumonia will be assessed by an infectious disease specialist using the Clinical Lung Infection Scale (CPIS). CPIS includes six criteria, including temperature, white blood cell count, tracheal secretion, oxygenation, culture and smear of tracheal secretion, and chest x-ray. Each of criteria is given a score of zero to two. The maximum score of this tool is 10. VAP is diagnosed if the sum of scores is equal to or greater than 6.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mehdi Ahmadinejad

Kerman University of Medical Sciences

mehdia50@gmail.com+98 34 3223 5011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026