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Comparative effect of nitroglycerin and misoprostol on cervical ripening before hysteroscopy

Comparative effect of nitroglycerin and misoprostol on cervical ripening before hysteroscopy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220203053929N1
Enrollment
84
Registered
2022-04-20
Start date
2022-04-21
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical ripening before hysteroscopy.

Interventions

Intervention group: nitroglycerin is used in post fornix vaginal for cervical ripening in nuli Gravid women who are candidate for hysteroscopy. In this double-blind clinical trial on 84 women in the a

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: : Conscious patient satisfaction, hysteroscopic women, lack of nitroglycerin sensitivity, without cardiovascular disease lack of existence of severe bleeding, as well as unstable status

Exclusion criteria

Exclusion criteria: Systolic blood pressure less than ?100 mm Hg, intravascular volume reduction, valvular heart disease, severe bleeding, multiparous (NVD 2 = Gravid,) impossibility of using nitroglycerin based on anesthesiologist's sensitivity to any food preservative) Use of hypertension or cardiac drugs for cerebral hemorrhage, anemia, glaucoma, hyperthyroidism, heart problems, heart failure, liver and kidney disease, hypotension and dissatisfaction with continuing the company

Design outcomes

Primary

MeasureTime frame
Cervical ripening, bleeding measurment, gravidity, parity, abortion number andside Effects like vomiting, hypotension, dizziness, stomach pain, diarehea, fever. Timepoint: Before hysteroscopy and after using Medicine ?and Side Effects after using. Method of measurement: Cervical dilation with measured dilator, bleeding Mount :pad percentage, pain score, weight :kg, gravidity :pregnancy count/parity:living birth delivery, sideeffect like diarehea, flushinv, hypotension, dizziness, headache, fever, nausea ??? vomiting.

Secondary

MeasureTime frame
Pain score and Mount of bleeding and dilation after hysteroscopy. Timepoint: Before hysteroscopy and after medications. Method of measurement: Pad percentage, pain score? measurment of dilation with measured dilator bouji.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahla mirgaloo bayat

Iran University of Medical Sciences

Melika.ansarin@gmail.com+98 21 4465 7764

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026