Reirradiation in pelvic malignancies

Effectiveness of reirradiation in disease control and symptom improvement; and urinary, gastrointestinal, cutaneous and soft tissue complications in patients with local recurrence of rectal, cervical and endometrial malignancies

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220130053877N1

Enrollment

Registered

2022-04-12

Start date

2022-03-21

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Local recurrence of rectal cancer in pelvis. Condition 2: Local recurrence of cervical cancer in pelvis. Condition 3: Local recurrence of endometrial cancer in pelvis. Malignant neoplasm of rectum Malignant neoplasm of cervix uteri Malignant neoplasm of endometrium

Interventions

Intervention group: Reirradiation for local recurrence of rectal, cervical and endometrial malignancies.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Local recurrence of rectum, cervix and endometrial cancer Inoperable patients or needs neoadjuvant reirradiation for better resection or adjuvant reirradiation for better control More than 6 month after previous course of radiation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Urinary complications. Timepoint: 1 week, 1 month, 3 month & 6 month after last session of reirradiation. Method of measurement: Common Terminology Criteria for Adverse Events (CTCAE) Version ?.?.;Gastrointestinal complications. Timepoint: 1 week, 1 month, 3 month & 6 month after last session of reirradiation. Method of measurement: Common Terminology Criteria for Adverse Events (CTCAE) Version ?.?.;Skin and soft tissue complications. Timepoint: 1 week, 1 month, 3 month & 6 month after last session of reirradiation. Method of measurement: Common Terminology Criteria for Adverse Events (CTCAE) Version ?.?.	—

Measure

Time frame

Urinary complications. Timepoint: 1 week, 1 month, 3 month & 6 month after last session of reirradiation. Method of measurement: Common Terminology Criteria for Adverse Events (CTCAE) Version ?.?.;Gastrointestinal complications. Timepoint: 1 week, 1 month, 3 month & 6 month after last session of reirradiation. Method of measurement: Common Terminology Criteria for Adverse Events (CTCAE) Version ?.?.;Skin and soft tissue complications. Timepoint: 1 week, 1 month, 3 month & 6 month after last session of reirradiation. Method of measurement: Common Terminology Criteria for Adverse Events (CTCAE) Version ?.?.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeed Araby aliabad

Shiraz University of Medical Sciences

araby.saeed69@gmail.com+98 71 3647 4320

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026