Major Depressive Disorder. Major depressive disorder, single episode
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: No treatmentt response to one trial of efficient dose with efficient duration Moderate and severe depression defined by Hamilton score under 17 Informed Consent Right- handedness Age above 18 and under 60
Exclusion criteria
Exclusion criteria: Suffering from major psychiatric disorders except simple phobia and nicotine dependency History of seizure in person or family Taking medications that lowers seizure threshold Risk of Suicide attempts Psychosis any magnetic or metal agent in he head or cardiac pacemaker Pregnancy No prior response to ECT
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of Hamilton depression rating scale. Timepoint: Prior to the study and 3 weeks later. Method of measurement: Hamilton Depression Rating Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Global Improvement. Timepoint: Prior to the study and 3 weeks later. Method of measurement: Clinical Global Impression questoinnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences