Fabrication and evaluation of the effect of lavender gum in the mouth

Fabrication and clinical study of the effect of lavender chewing gum on salivary Streptococcus mutans, salivary pH, plaque index, and gingival bleeding

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220122053799N1

Enrollment

Registered

2022-03-05

Start date

2022-04-03

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries. Arrested dental caries

Interventions

Intervention 1: Intervention group: Chewing lavender gum by extracting the plant by percolation method using 70% ethanol made in Tabriz Medical Research Center. The amount of gum used per person is si

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Participants do not have systemic disease Have acceptable oral hygiene (no clear mass and plaque) Age range 18 to 65 years Do not be pregnant or breastfeeding Having an average of 22 teeth

Exclusion criteria

Exclusion criteria: Taking antibiotics or drugs that affect saliva Use oral appliance Smoking and alcohol consumption People with temporomandibular joint problems

Design outcomes

Primary

Measure	Time frame
Gingival bleeding rate. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: Bleeding index using periodontal prop in Salcus at four levels (labial, Lingual and Interproximal).;Check the percentage of license plate index. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: Plaque detector tablets.;Measurement of the number of Streptococcus mutans saliva colonies. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: The patient will be asked to collect saliva in the mouth for one minute and then pour it into a sterile Falcon graduated tube. To determine the number of Streptococcus mutans colonies, they should be sent to the microbiology laboratory and incubated in the specific medium of Mitis salivarius agar at 37 ° for 2 days and Streptococcus mutans were counted.;Saliva pH. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: PH meter.	—

Measure

Time frame

Gingival bleeding rate. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: Bleeding index using periodontal prop in Salcus at four levels (labial, Lingual and Interproximal).;Check the percentage of license plate index. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: Plaque detector tablets.;Measurement of the number of Streptococcus mutans saliva colonies. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: The patient will be asked to collect saliva in the mouth for one minute and then pour it into a sterile Falcon graduated tube. To determine the number of Streptococcus mutans colonies, they should be sent to the microbiology laboratory and incubated in the specific medium of Mitis salivarius agar at 37 ° for 2 days and Streptococcus mutans were counted.;Saliva pH. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: PH meter.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Kooh Soltani

Tabriz University of Medical Sciences

mkoohsoltani@yahoo.com+98 41 3335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026