Dosage of enoxaparin in the treatment of neonatal thrombosis.
Conditions
Interventions
Intervention 1: Preterm babies who receive a dose of enoxaparin 2 mg/kg twice a day subcutaneously. Intervention 2: Preterm infants who receive a dose of enoxaparin 1.7 mg/kg twice a day subcutaneousl
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 30 Days
Inclusion criteria
Inclusion criteria: Neonatal thrombosis Thrombosis confirmed by color Doppler ultrasound or MRV spiral CT scan or angiography Consensus of the treatment team to start anticoagulant treatment
Exclusion criteria
Exclusion criteria: Platelet count less than 50,000 Active bleeding High risk of bleeding if anticoagulants are used Creatinine higher than 1.5 times normal for age and sex Liver failure that can interfere with the synthesis of coagulation factors and increase the risk of bleeding. History of heparin sensitivity Heparin-induced thrombocytopenic syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Elimination of thrombus determined by ultrasound. Timepoint: The first 30 days of life. In infancy. Method of measurement: Anti-Xa factor.By blood sampling method;Ultrasound to check for thrombosis.;Factor antiXa;. Timepoint: The first 30 days of life. Method of measurement: measurement by blood sampling. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFaezeh Ghofranipour
Shahid Beheshti University of Medical Sciences
Outcome results
None listed