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Evaluation of the effect of combination training and ISO supplementation in dialysis patients

Interactive effect of ISO protein consumption and eight weeks of combined training during dialysis on serum levels of hepcidin , interleukin-6, iron , ferritin and renal function indices, body fat percentage, lipid profile, glycemic index and MIS and DMS scale in hemodialysis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220121053779N1
Enrollment
35
Registered
2022-03-05
Start date
2022-03-15
Completion date
Unknown
Last updated
2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease. Chronic kidney disease (CKD)

Interventions

Intervention 1: Intervention group: In the supplement-activity group, the subjects were trained for 8 weeks at the end of each dialysis session (3 sessions per week). Or 24 grams in 150 cc of water wi

Sponsors

University of Sistan and Baluchestan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 55 Years

Inclusion criteria

Inclusion criteria: Hemodialysis 3 times a week Body mass index 35-18/5 kg / m2, At least 6 months on hemodialysis treatment, Absence of severe respiratory and heart failure, chronic inflammatory disease of unknown origin, dementia, cancer, hepatitis B, C, neurological disease, HIV Do not use oral supplements and intravenous nutrition No history of recent surgery in the last quarter Range age 25-55 years

Exclusion criteria

Exclusion criteria: Lack of cooperation of the patient to implement the research protocol, including failure to perform at least two sessions of exercise or lack of supplementation by the patient

Design outcomes

Primary

MeasureTime frame
Serum levels of interleukin-6. Timepoint: Measurement of interleukin-6 levels at the beginning of the study and after 8 weeks of protocol implementation. Method of measurement: Using blood samples with ELISA technique.;Serum levels of hepcidin. Timepoint: Measurement of hepcidin levels at the beginning of the study and after 8 weeks of protocol implementation. Method of measurement: Using blood samples with ELISA technique.;Glycemic indexes include fasting blood sugar, insulin and insulin resistance. Timepoint: Measurement at the beginning of the study and after 8 weeks of protocol implementation. Method of measurement: Using blood samples with ELISA technique.;Lipid profile. Timepoint: Measurement at the beginning of the study and after 8 weeks of protocol implementation. Method of measurement: Using blood samples with ELISA technique.;Kidney function indicators. Timepoint: Measurement at the beginning of the study and after 8 weeks of protocol implementation. Method of measurement: Using blood samples with ELISA technique.;Serum iron levels. Timepoint: Measurement at the beginning of the study and after 8 weeks of protocol implementation. Method of measurement: Using blood samples with ELISA technique.;Serum ferritin level. Timepoint: Measurement at the beginning of the study and after 8 weeks of protocol implementation. Method of measurement: Using blood samples with ELISA technique.;The rate of malnutrition. Timepoint: At the beginning of the study and after 8 weeks of protocol implementation. Method of measurement: Using the Malnutrition-Inflammation Questionnaire.;Percentage of body fat. Timepoint: At the beginning of the study and after the end of the study. Method of measurement: Using a caliper.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Sargol Hossein Zadeh

The University of Sistan and Baluchestan

Elhamhosseinzadeh22@gmail.com+98 54 3222 6807

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026