The effect of adding dexamethasone to lidocaine in infraclavicular block on the onset and duration of block

Evaluating the Effect of adding Dexamethasone to Lidocaine 1.5% in Infraclavicular Block with Ultrasound Guide on the Onset of Effect and Duration of Block

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220120053774N1

Enrollment

Registered

2022-02-05

Start date

2022-03-21

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper limb fractures. Injuries to the elbow and forearm

Interventions

Intervention 1: Intervention group: 33 ml of 1.5% lidocaine solution (495 mg) and 2 ml of dexamethasone (Dexadic - Caspian Supply Pharmaceutical Company) (8 mg) will be used for Infraclavicular Block

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18 to 60 years old ASA classification Status 1 and 2 Need to orthopedic surgery to repair an upper limb fracture (below the arm)

Exclusion criteria

Exclusion criteria: Coagulation disorder (INR> 1.4) History of liver, kidney, peptic ulcer disease History of uncontrolled diabetes Infection in the area of nerve block History of hypersensitivity to local anesthetics or dexamethasone History of long-term use of corticosteroids History of addiction or narcotic use Pregnancy Changing the anesthesia plan during surgery from nerve block to general anesthesia Hemodynamic instability Patient request to leave the study

Design outcomes

Primary

Measure	Time frame
The onset of analgesia. Timepoint: Every 5 minutes to complete block. Method of measurement: Using a question from the patient and using a pinprick test, using a needle with mild skin irritation (normal sense of zero score, inability to understand pinprick score 1 and lack of sense of touch score 2) will be used. To ensure analgesia, a score of 1 sensory block is acceptable. The patient's sensory block is assessed and the patient's onset of analgesia is recorded in a questionnaire. Motion block is also measured using a modified bromage scale. In this way, points are given from zero to 4 (full strength of related muscles, score 4, decrease in muscle strength but the ability to move against resistance 3, ability to move against gravity 2, slight muscle jump 1 and inability to move zero score).;The ?duration of analgesia. Timepoint: Every 5 minutes to 30 minutes after injection of block solution, during surgery and then every 30 minutes until complete removal of sensory and motor block in recovery and ward. Method of measurement: Pain in the recovery ward using the Visual Analogue Scale (VAS), which is a numerical scoring scale (zero painless to 10 highest pain).	—

Measure

Time frame

The onset of analgesia. Timepoint: Every 5 minutes to complete block. Method of measurement: Using a question from the patient and using a pinprick test, using a needle with mild skin irritation (normal sense of zero score, inability to understand pinprick score 1 and lack of sense of touch score 2) will be used. To ensure analgesia, a score of 1 sensory block is acceptable. The patient's sensory block is assessed and the patient's onset of analgesia is recorded in a questionnaire. Motion block is also measured using a modified bromage scale. In this way, points are given from zero to 4 (full strength of related muscles, score 4, decrease in muscle strength but the ability to move against resistance 3, ability to move against gravity 2, slight muscle jump 1 and inability to move zero score).;The ?duration of analgesia. Timepoint: Every 5 minutes to 30 minutes after injection of block solution, during surgery and then every 30 minutes until complete removal of sensory and motor block in recovery and ward. Method of measurement: Pain in the recovery ward using the Visual Analogue Scale (VAS), which is a numerical scoring scale (zero painless to 10 highest pain).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzad Sarshivi

Sanandaj University of Medical Sciences

farzadsarshivi@gmail.com+98 87 3361 1231

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026