Mild cognitive impairment (MCI) is a common condition in the elderly characterized by impaired memory, attention, and cognitive function with regard to person's age and education. More specifically, MCI is characterized by cognitive complaint by the patient or his family, report of cognitive decline (compared to last year), the presence of obvious cognitive impairment with evident clinical evaluation, the absence of major problems in daily life and the absence of dementia..
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age more than 55 years Mild cognitive impairment should be diagnosed by neurologist or psychiatrist according to these items: cognitive complaints coming from the patients or their families, the reporting of a decline in cognitive functioning relative to previous abilities during the past year by the patient or informant, cognitive disorders as evidenced by clinical evaluation(impairment in memory or in another cognitive domain), absence of major repercussions on daily life, absence of dementia Initial Montreal Cognitive Assessment (MoCA) between 21 and 25
Exclusion criteria
Exclusion criteria: Addiction or alcohol abuse Another chronic neurologic condition such as drug-resistant epilepsy, Parkinson's disease, dementia (lewy body dementia, vascular dementia, Alzheimer's disease, frontotemporal dementia , etc.), stroke, etc. Psychologic conditions such as Psychosis, personality disorder, major depressive disorder, etc. History of moderate to severe brain injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual-spatial function: includes the cognitive processes necessary to "identify, integrate and analyze space and visual form, details, structure and spatial relationships" in more than one dimension. Spatial visual skills are required for movement, depth and distance perception, and spatial navigation. Timepoint: before intervention, after (1-month) intervention and 1 month after the end of intervention period. Method of measurement: Addenbrooke's Cognitive Examination III, Integrated Cognitive Assessment(ICA).;Verbal memory: refers to the ability of memory to store information verbally. Vocabulary definitions, key details in a story, or the name of a species of living thing are all examples of verbal memory. Timepoint: before intervention, after (1-month) intervention and 1 month after the end of intervention period. Method of measurement: Integrated Cognitive Assessment(ICA).;Attention: It is the behavioral and cognitive process of selective focus on one aspect of information, whether subjective or objective, while ignoring other comprehensible information. Timepoint: before intervention, after (1-month) intervention and 1 month after the end of intervention period. Method of measurement: Addenbrooke's Cognitive Examination III.;Executive Performance: A set of mental skills that include working memory, flexible thinking, and self-control. Timepoint: before intervention, after (1-month) intervention and 1 month after the end of intervention period. Method of measurement: Addenbrooke's Cognitive Examination III.;Verbal psychology: A cognitive function that refers to retrieving information from memory. Timepoint: before intervention, after (1-month) intervention and 1 month after the end of intervention period. Method of measurement: Addenbrooke's Cognitive Examination III.;Linguistic function: refers to a person's ability to use sign language. So that one can understand the meaning and also convey it. Timepoint: before intervention, after (1-month) intervention and | — |
Secondary
| Measure | Time frame |
|---|---|
| Walking speed: The basic criterion for walking is the initial ability of a person to walk. Walking speed shows us the time required to traverse a certain distance. Timepoint: before intervention, after (1-month) intervention and 1 month after the end of intervention period. Method of measurement: 10m dynamic walking speed test.;Gait ability: It is a measured to assess the patient's health in terms of walking which criterion such as the length and height of the step, the appearance of walking, symmetry of steps, continuity of steps, deviation from the path, walking speed, etc. are taken considered. Timepoint: before intervention, after (1-month) intervention and 1 month after the end of intervention period. Method of measurement: Tinetti test.;Balance : It is an ability to maintain the line of gravity (vertical line from center of mass) of a body within the base of support and it is essential for success in performing daily life tasks. Timepoint: before intervention, after (1-month) intervention and 1 month after the end of intervention period. Method of measurement: ??? ?????.;Life quality: It is the degree to which a healthy person is comfortable and can participate in or enjoy life events. Timepoint: before intervention, after (1-month) intervention and 1 month after the end of intervention period. Method of measurement: SF-36 questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences