The effect of probiotic supplement on reducing oxidative stress and sperm quality in patients with asthenospermia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220119053769N1

Enrollment

Registered

2022-01-28

Start date

2021-09-11

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthenospermia. Male infertility

Interventions

Intervention 1: Intervention group: FAMILACT probiotic with a dose of 109 CFU. Intervention 2: Control group: Plasbo.

Eligibility

Sex/Gender

Male

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: People with asthenospermia and infertility problems due to abnormal sperm motility

Exclusion criteria

Exclusion criteria: People outside the age group of 18-40 People who take certain medications to treat infertility People on a diet rich in probiotics People with asthenospermia who are forced to take certain medications during the illness

Design outcomes

Primary

Measure	Time frame
Sperm and semen parameters. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram.	—

Secondary

Measure	Time frame
Measurement of malondialdehyde (MDA) semen. Timepoint: Before intervention and after intervention. Method of measurement: Eliza.;DNA fragmentation index test. Timepoint: Before intervention and after intervention. Method of measurement: Using Acidic Aniline Blue staining.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ghazaleh Meshkdanian

Kashan University of Medical Sciences

g_moshkdanian@yahoo.com+98 31 5544 3022

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026