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Comparison of the therapeutic effects of four topical drugs in the treatment of vitiligo

Comparison of the therapeutic effects of four topical drugs on patients with vitiligo referred to the dermatological clinics of Isfahan University of Medical Sciences

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220117053743N2
Enrollment
60
Registered
2022-05-09
Start date
2022-03-06
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo. Vitiligo

Interventions

Intervention 1: Intervention group: clobetasol 0.05% (Raha Pharmaceutical Co., Iran) daily on the lesions remaining for at least 3 hours while avoiding direct sun exposure. Intervention 2: Interventio

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 16-60 years Involvement of <20% total body surface area Lesions on the extremities, trunk, and face

Exclusion criteria

Exclusion criteria: Follicular pigmentation White hair in the lesion Lesions at the distal end of the extremities Genital, periungual, and skin fold lesions Topical treatment or phototherpay within the past month Pregnancy

Design outcomes

Primary

MeasureTime frame
Perifollicular pigmentation improvement. Timepoint: Three months after the initiation of treatments. Method of measurement: 1) mild: 0-25%, 2) moderate: 26-50%, 3) good: 50-75%, 4) excellent: >75%.

Secondary

MeasureTime frame
Patient satisfaction with treatments. Timepoint: Three months after the initiation of treatments. Method of measurement: Visual Analogue Scale.;Side effects. Timepoint: During treatments. Method of measurement: Patient reports of observation by the specialist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAida Farmani

Esfahan University of Medical Sciences

aida.farmani.med@gmail.com+98 31 3261 6408

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026