Skip to content

Evaluation of the effect of paracetamol with Entonox in comparison with pethidine with Entonox on labor pain

Evaluation of the effect of paracetamol with Entonox in comparison with pethidine with Entonox on labor pain

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220116053734N1
Enrollment
100
Registered
2022-12-08
Start date
2022-12-22
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain during labor.

Interventions

Intervention 1: first Intervention group: Infusion of acetaminophen, 1 g, 6.7 ml, Caspian company, in 100cc of N/S, with 300 gtt/min + entonox gass inhalation. Intervention 2: second Intervention grou

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Patients should be between 18 and 45 years old. The fetal presentation should be cephalic. Fetuses are single. Dilatation of the uterus should be 4 cm.

Exclusion criteria

Exclusion criteria: Having a fetal growth disorder Having a history of chronic pain Having an addiction to drugs, alcohol and smoking Having indications for cesarean section Havind a history of severe psychological disorders, cardiovascular, renal, respiratory, asthma, diabetes, hypertension, coagulation disorders and epilepsy in mother

Design outcomes

Primary

MeasureTime frame
Labor pain score. Timepoint: before drug injection and 15, 30, 45, 60 and 120 minutes after drug injection. Method of measurement: pain NRS numerical rating scale.

Secondary

MeasureTime frame
The time between drug injection and delivery. Timepoint: Drug injection time and fetus delivery time. Method of measurement: time.;Placenta delivery time. Timepoint: delivery time and placenta delivery time. Method of measurement: time.;Newborn Apgar score. Timepoint: 1 and 5 minutes after labor. Method of measurement: Apgar score.;Mother hemoglobin level. Timepoint: Before delivery and 6 hours after delivery. Method of measurement: Hemoglobin.;Drug side effects in the mother including headache/dizziness/blurred vision/dry mouth/nausea/vomiting/dyspnea. Timepoint: During the time of drug injection until delivery. Method of measurement: Ask the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEnsiyeh Rajabpour

Qazvin University of Medical Sciences

medicine@qums.ac.ir+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026