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Evaluation of protective effect of Royal Jelly on Serum Oxidative Stress markers and Interleukin-1 Beta of Patients with Multiple Sclerosis.

Evaluation of protective effect of Royal Jelly on Serum Oxidative Stress markers and Interleukin-1Beta of Patients with Multiple Sclerosis.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220116053732N1
Enrollment
60
Registered
2022-05-08
Start date
2022-03-06
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MS disease. Multiple sclerosis (of):NOS brain stem cord disseminated generalized

Interventions

Intervention 1: The intervention group included people with MS who on the first day of the study and on the 50th day of the study "after swallowing a capsule containing 350 mg of royal jelly lyophiliz

Sponsors

Dezfoul University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age of patients should be 20-45 The sub type of M.S should be "Relapsing-Remitting MS" (RRMS). The diagnosis of "RRMS" is confirmed by a neurologist based on neurological examination and imaging. Patients should be treated with "Interferon" for at least 6 months.

Exclusion criteria

Exclusion criteria: Patients with anemia, Chronic Heart Disease, lung disease, Diabetic mellitus, Autoimmune diseases such as Rheumatoid Arthritis, SLE, ... Patients treated with corticosteroids or ACTH. Use of any supplements by patients. History of asthma and allergies in the patient. Occurrence of allergic symptoms during the study Occurrence of a "MS" attack during the study period. The patient' s refuse to continue study.

Design outcomes

Primary

MeasureTime frame
The rate of change of oxidative stress state. Timepoint: Evaluation of "oxidative stress status" at the beginning of the study and on day 30 after the use of Royal Jelly. Method of measurement: The assay of Malondialdehyde , Superoxide dismutase, Catalase, Nitric oxide.

Secondary

MeasureTime frame
Expanded Disability Status Scale. Timepoint: Study of "Expanded Disability Status Scale" at the beginning of the study and on day 30 after the use of Royal Jelly. Method of measurement: Scoring from zero (best condition) to 10 (death due to MS) according to the neurologist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Susan Sabbagh

Dezfoul University of Medical Sciences

sabbaghsusan@yahoo.com+98 61 4222 2709

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026