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Evaluation of the clinical effect of Methylprednisolone lozenge in oral lichen planus

Evaluation of the effect of Methylprednisolone lozenge to improve symptoms of patient with oral lichen planus: An experimental study and a double-blinded randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220115053724N1
Enrollment
40
Registered
2022-09-23
Start date
2022-09-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral lichen planus disease. Other lichen planus

Interventions

Intervention 1: Intervention group: including 20 patients who are diagnosed with oral lichen planus patients is based on the examination of the patient by a dentist specializing in oral and dental dis

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18 to 60 years Willingness to participate in the study and complete the ethical consent form Women should not be pregnant or lactating Not using allopurinol Not using viral vaccines during treatment Patients do not have a confirmed history of allergic reactions following the oral intake of methylprednisolone The patient does not have a low level of consciousness The patient should not be treated with warfarin The patient does not have an active viral disease

Exclusion criteria

Exclusion criteria: Aggravation of oral lichen lesions Unwillingness to cooperate during treatment Not using medicine for two consecutive days Emergence of allergic reaction to methylprednisolone

Design outcomes

Primary

MeasureTime frame
Redness and inflammation. Timepoint: At the beginning of treatment and after every 2 to 10 days, the status of oral lichen planus lesions is evaluated for the severity of redness and inflammation (score 0 to 4). Method of measurement: Scoring severe redness and inflammation using a Reeda questionnaire.;Severe pain and burning. Timepoint: At the beginning of treatment and after every 2 to 10 days, the condition of oral lichen planus lesions is evaluated for the severity of pain and burning (score 0 to 4). Method of measurement: Scoring Severe pain and burning using VAS questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Kushki

Ahvaz University of Medical Sciences

javaddorton@yahoo.com+98 21 6624 5047

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026